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Insulin Resistance

Insulin is a hormone produced by pancreatic b-cells and plays a key role in regulating glucose homeostasis.1 Normally, pancreatic b-cells secrete insulin in response to rising levels of blood glucose. Insulin, by predominantly acting on liver, muscle, and adipose tissues, allows the body to take up, store, and use these glucose molecules as energy. Insulin resistance is the impaired biological response to...

Prescribed Medications for Type 2 Diabetes Mellitus

Glycemic control and cardiovascular risk factor management are priority considerations when choosing a treatment for type 2 diabetes mellitus (T2DM).1 The American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) emphasize the importance of making significant lifestyle modifications such as eating a healthy diet and exercising for all individuals with T2DM. At the...

Blood Glucose Meter Accuracy

What is the Standard for Determining Blood Glucose Meter Accuracy? The International Organization for Standardization (ISO) determines specifications for various products, including blood glucose meters (BGMs).1 BGMs need to fulfill certain criteria to meet its latest standard of ISO 15197:2013, listed below: For blood glucose levels >100 mg/dL, 95% of data pairs (ie, reference measurement and BGM measurement) must...

Mental Health and Diabetes

Diabetes mellitus is a complex chronic disease that requires constant self-management and is known to pose psychological and emotional burdens, placing affected individuals at a higher risk of developing diabetes distress, depression, and anxiety, along with other mental disorders.1–3 Nevertheless, with proper diagnosis and early treatment, diabetes-related mental health disorders can be effectively managed.

Sugar Alcohols

Sugar alcohols, also known as polyols (referring to their chemical structures), are hydrogenated mono-, di-, and polysaccharides.1 They are commonly used as natural alternative sweeteners and bulking agents.2,3 Unlike artificial sweeteners (eg, aspartame, sucralose, and saccharin), sugar alcohols provide some caloric value and are naturally present in some fruits and vegetables in small amounts.1,2 They are also commercially produced in...